Role of type of diet and life style on chronic inflammatory marker

 

 

Abstract              Background: Subclinical chronic inflammation plays a key role in the development of atherosclerosis, a key factor in the initiation of CVDs. Biomarkers of inflammation are therefore considered predictors of future CVD events. CRP is an acute-phase protein and is one of the most sensitive and most recurrent markers of inflammation. Many studies have shown that an increase in the concentration of HSCRP is associated with an increased risk of CVDs in different populations around the world. Material and Methods: Total 50 subjects of both sexes who were healthy but having BMI > 25, were recruited for this study. At the time of enrollment, each volunteer was given health history Questionnaire. Based on that we classified the subjects in two groups according to their type of diet (Vegetarian vs. Non vegetarian) and life style (sedentary vs. Non sedentary). Blood samples collected for fasting HSCRP values and then appropriate statistical test applied for interpretation of results. Observations and Results: Statistical analysis did not show any statistically significant correlation of type of diet with HSCRP value (non-vegetarian: vegetarian diet ratio of HSCRP was 2.21: 2.14, z value 0.77, P value > 0.1251) while, there was statistically significant correlation found for lifestyle with HSCRP value (sedentary: non sedentary lifestyle ratio of HSCRP was 2. 43: 1.80, z value 21, P < 0.05).

Key Word: HSCRP, Life Style, Vegetarian Diet, Chronic Inflammation.