Assessment of prognosis in acute myocardial infarction in correlation with Killip class on day 0, day 3, day 7

 

Triveni Ayyanna¹, Ashok Thaned^2*

 

Abstract              Background: Acute myocardial infarction (AMI) is one of the most common diagnoses in hospitalized patients in industrialized countries. World-wide, approximately 650,000 patients experience a new AMI and 450,000 experience a recurrent AMI each year. Aims and Objectives: A study of Assessment of prognosis in acute myocardial infarction in correlation with Killip class on day 0, day 3, day 7. Methodology: This Single center prospective study carried out in Karnataka institute of medical sciences Hubli. A total of 100 patients of AMI admitted to Medical wards and ICCU department of Department of Medicine were included in the study All patients of age Age >18 yrs. The statistical analysis was done by paired and unpaired t-test and co-relation calculated by SPSS 19 version software. Result: Out of 13 patients who belonged to killip class 4 on day 0, 6 patients expired during 7 day follow up. It is statistically significant i.e. Patients in killip class 4 have a poor prognosis after acute myocardial infarction. On day 3, 2 patients who were in killip class 3 expired during 7 day follow up .Four patients were in killip class 4 on day 3. All six patients expired between day 3 and day 7 of follow up. I.e. all patients who have expired belonged to higher killip class (3 or 4) with higher mean uric acid. This scatter plot shows that when the serum uric acid level on the day of admission was correlated with CK-MB values, a strong positive correlation was obtained, that is, as the value of one increases the other also increases as shown in this scatter plot. Conclusion: From our study, we conclude that SUA levels are correlated with Killip Class and patients with higher Killip Class have higher SUA levels in AMI. Hyperuricemia is an indicator of poor prognosis in acute myocardial Infarction. Serum uric acid can be used as a marker of short-term mortality in acute myocardial infarction.

Key words: Killip Class, Serum Uric Acid (SUA), Prognosis of MI