Study of hyponatremia as prognostic indicator in acute ST elevation myocardial infarction

 

 

Abstract              Background: Myocardial infarction causes more deaths and disability and incurs greater economic costs than any other illness in the world. It is the most common, serious chronic, life threatening illness. Aim and objective: To study the prognostic importance of hyponatremia in acute ST elevation myocardialinfarction. Methodology: 100 consecutive patients presenting with acute ST- elevation myocardial infarction admitted to Bapuji Hospital and Chigateri General Hospital attached to JJM Medical college, Davanagere, from December 2014 to November 2016 were studied. Qualifying patients underwent detailed history and clinical examination. Plasma sodium concentrations were obtained on admission and at 24, 48 and 72 hours thereafter. The primary end point was all cause mortality within 30 days following myocardialinfarction. Results and discussion: In our study substantial proportion of patients who presented with acute ST elevation myocardial infarction were hyponatremic on admission or developed hyponatremia shortly after admission. Univariate and Multivariate analysis showed hyponatremia on admission or early development of hyponatremia as a significant independent predictor of 30 day mortality.

Key Word: hyponatremia, prognostic indicator.