Lipid profile among newly detected cases of coronary heart disease

 

 

Abstract              Background: Burden of coronary heart disease is constantly increasing in the past few decades. There are extensive epidemiological data demonstrating that high blood cholesterol levels increase cardiovascular risk, and that this risk is dependent on levels of the different blood cholesterol fractions. Moreover, the reduction of total blood cholesterol has been clearly related to a reduction in the risk of stroke, coronary disease and overall cardiovascular death. Hence, this Study was planned to assess the pattern of fasting lipid profile among newly detected cases of Coronary Artery Disease. Methods: A cross-sectional study was conducted among newly detected coronary artery disease patients in a tertiary care teaching hospital from April 2015 to March 2016. A total of hundred patients were included. Following collection of detailed history, venous blood samples were collected from all participants and it was assessed for Fasting blood sugars, Fasting lipid profile, post prandial blood sugars and HbA1c. Data was analysed using SPSS software. Results: Findings of this study shows that higher levels of total cholesterol, LDL and triglycerides were reported among the newly diagnosed cases of coronary heart disease and at the same time HDL levels was found to be lower among them. Conclusions: LDL-C and triglycerides are established in clinical practice as important tools in risk prediction and therapy follow-up. The importance of checking these measurements at regular periodic intervals should be made aware to the patients in order to prevent the complication that occurs due to it.

Key Word: Coronary artery disease, Lipid profile, LDL, HDL.