Prevalence of non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus and its correlation with the complications in a tertiary care hospital of southern Tamil Nadu

 

 

Abstract              Background: Non alcoholic fatty liver disease (NAFLD) is a relatively common and “silent” disease, which has gained special attention over the recent years, due to its serious impact on public health being appreciated increasingly. Despite the exponential increase in the research going on in this field, still there are various queries which remain unclear. In this study the prevalence of non alcoholic fatty liver disease in patients with type 2 diabetes mellitus is studied Methodology: 100 patients with type 2 diabetes were included in the study. They were screened for NAFLD using ultrasound abdomen. Serum triglycerides was checked. Correlation between the triglycerides and fatty liver was analysed. Informed consent was obtained from all the individuals. The participants were selected from out patients attending the medical and medical gastroenterology outpatient clinic and in patients admitted in the medical ward. Results: In this study the prevalence of non alcoholic fatty liver disease was found to be 65%.those patients found to have Non-alcoholic fatty liver disease, also found to have elevated non HDL C. Serum triglycerides were normal in patients who don’t have fatty liver disease. Conclusion: In our study, we found that all patients with non alcoholic fatty liver disease, had elevated triglycerides with 100% correlation. Non HDL-C is a better predictor of cardiovascular risk and steato hepatitis in patients with NAFLD. Hence lowering Non HDL cholesterol has a beneficial role in the treatment. Early diagnosis and treatment of NAFLD can reduce cardiovascular risk in patients with diabetes.

Key Word: fatty liver disease.