A cross sectional hospital based study of assessment of clinical and biochemical parameters of acute pancreatitis

 

Abstract              Background: Pancreatitis defined as the inflammation of the pancreas and is always, associated with acinar cell injury. (Singer et al) Acute pancreatitis is clinically characterized by acute onset of abdominal pain and a rise in the activity of pancreatic enzymes in the blood and urine.1 Most attacks have a benign course but severe attacks may lead to shock, renal failure, respiratory failure and death. Materials and Methods: The present study was a cross sectional study hospital based carried out among 60 indoor cases of acute pancreatitis admitted under department of general medicine in a tertiary healthcare teaching institute in Telangana during February 2018 to April 2018. All the cases of suspected acute pancreatitis admitted under department of general medicine in a tertiary healthcare institute, and fulfils the set inclusion criteria, who consented to participate in the study were included in the present study. Results: In this study it was observed that 51.66% patients had a history of chronic alcoholism, 23.33% patients had history of smoking. It was found that 61.66% of study participants were having mixed pattern of diet, while 28.33% study participants were having strict vegetarian pattern of diet (Table 3). Conclusion: Early assessment of severity and intensive care management of acute pancreatitisis of paramount importance. Lab markers especially high values of lipase and other markers could be important prognostic markers for predicting morbidity and mortality in acute pancreatitis.

Key Words: Pancreatitis, acinar cell injury, morbidity, mortality