A study of clinical and laboratory profile of dengue fever patients at tertiary health care center

 

Rajaram L Munde¹, Chetan R Sarda^2*

 

¹Assocoate Professor, ²Assistant Professor, Department of Medicine, MIMSR Medical College, Latur, Maharashtra, INDIA.

 

Abstract              Background: Dengue is the most extensively spread mosquito-borne disease, transmitted by infected mosquitoes of Aedes species. Aims and Objectives: To study clinical and laboratory profile of dengue fever patients at tertiary health care center. Methodology: This was a cross-sectional study carried out in the patients who presented with fever and clinical features suspected of dengue during the one year period i.e. May 2018 to May 2019 during the one year period. All details of the patients like age, sex, clinical feature and all routine laboratory test were done like CBC, Peripheral smear for Platelets, PS for Malaria parasite, NS 1 antigen for dengue etc. The data was entered to excel sheet and analyzed by SPSS 19 version software. Result: In our study we have seen that The majority of the patients were in the age group of 20-30 were 34.15%, followed by 30-40 were 30.49%, 40-50 were 15.85%, 50-60 were 10.98%, >60 were 8.54%. The majority of the patients were Male i.e. 63.41% and Female were 36.59% The most common clinical features were Fever in 100.00%, followed by Headache in 96.34%, Retro orbital pain in 90.24%, Generalized body ache in 84.15%, Joint pain in 76.83%, Abdominal pain in 64.63%, Rash in 35.37%, Bleeding manifestations in 32.93%, HypotensionIn 25.61%, decreased urine output in 23.17%, Tachycardia in 15.85%, Epi gastric tenderness in 13.41%. The most common laboratory features were Thrombocytopenia (<50000/cumm) in 64.63%, Leucopenia (<4000/cumm) in 30.49%, Raised AST/ALT (>45IU/L) in 87.80%, Raised Hematocrit (>45%) In 15.85%. Conclusion: It can be concluded from our study that the majority of the patients were having the clinical features like fever, Headache , Retro orbital pain The most common laboratory features were Thrombocytopenia, Leucopenia, Raised AST/ALT etc.

Key Word: Thrombocytopenia, AST/ALT, NS 1 antigen, Dengue fever .