Cross sectional study on clinico-investigative profile of dengue fever with context to thrombocytopenia

 

 

Abstract              Background: India is one of the seven identified Southeast Asian countries reporting frequent outbreaks of the dengue with case fatality rates as high as 3-5%. Dengue has an extensive clinical presentation ranging from fever to fatal bleeding and shock, often with an unexpected mortality. Objective: To study clinico-investigative of dengue fever with context to thrombocytopenia. Material and Method: This was descriptive cross sectional study conducted at tertiary care medical teaching hospital of western Maharashtra. Total 200 patients were included in present study as per inclusion and exclusion criteria. Purposive sampling method was used in this study. Structured and pilot tested questionnaire used for data collection. Results. Prevalence of dengue in present study was found to be 4%. Out of 200 patients maximum (53.5%) were in the age group of 15 to 30 years of age and male predominance was seen. In present study out of all patients 97.5% (195) survived where as 2.5% (05) succumbed to dengue. Statistical significant difference was observed in mean hematocrit value of mild and severe thrombocytopenic patients. Most common symptoms observed in current study were headache (77%) and myalgia (76.5%). Mean hospital stay of mild thrombocytopenic patients was 5.92±2.09 days while moderate and severe thrombocytopenic patients mean hospital stay was 6.2±2.74 days and 7.03±3.3 days respectively. Conclusion: The distribution patterns of clinical and laboratory criteria observed did not differ substantially from those described in the literature. Hematocrit and level of thrombocytopenia indicate the prognosis in terms of hospital stay of patients suffering from dengue.

Key words: Dengue, Thrombocytopenia, Fever, Hematocrit, Dengue hemorrhagic fever.