A study of atrial volume and it’s determinants as prognostic factor in patients with dilated cardiomyopathy

 

 

Abstract              Background: Cardiomyopathy is a complex disease process that can affect the heart of a person of any age. Cardiomyopathy is an important cause of morbidity and mortality among the world's aging population. The utility of LA volume and function for monitoring cardiovascular risk and for guiding therapy is an evolving science and may prove to have a very important public health impact. Aim and objective: To study the atrial volume and it’s determinants as prognostic factor in patients with dilated cardiomyopathy Methodology: Present study was prospective study carried out on 50 Patients with diagnosis of Congestive Heart failure. Study period May 2018 to April 2019. The left atrial functions of the patients were evaluated by performing transthoracic echocardiography. The LV ejection fraction, LV volumes, and LV mass were determined for a total number of three times; first at the time of the visit to the hospital, and then at end of first and sixth months of follow up. Data was analysed with appropriate statistical tests. Results: Patients with DCM showed a larger LA VOLUME (75.57 ± 27.60 ml,) compared with normal control subjects (58.57 ± 21.37 p < 0.016). Differences in the E-wave velocity (0.92 ± 0.25 vs. 1.07 ± 0.20; p <0.029), A-wave velocity (0.68 ± 0.32 vs. 0.82 ± 0.16 p < 0.066), E/A ratio (1.71 ± 0.90 vs. 1.30 ± 0.25 p < 0.05), or DT (165 ± 40.11 vs.197.25± 24.33 p <0.002) were observed between patients and control subjects.

Key Word: atrial volume, prognostic factor.