A study of non-motor symptoms in parkinson’s disease

 

Deepali Bhagwan Aendole^1*, Anita Gaule²

 

Abstract              Background: Parkinson’s Disease is reported to be the second most common neurodegenerative pathology of the central nervous system. PD are often under-recognized by treating physicians yet have significant impact on disability and health-related quality of life, particularly in advanced disease. NMS leads to severe disability affecting quality of life of patients. Aim and objective: To study the non motor symptoms of Parkinson’s disease Methodology: Present study was a cross sectional study carried out in 100 patients with parkinson’s disease (PD). Data was collected with pretested questionnaire. Data included demographic data and clinical history. The Hoehn and Yahr (HandY) stage was used to measure disease severity. The non-motor symptom scale (NMSS) was used to assess NMS. Data was analysed with appropriate statistical tests. Results and discussion: Thus the prevalence of NMS was 96%. Most frequent non motor symptom was difficulty in falling asleep (55%) followed by urinary frequency (42%) and nocturia (37%). Most frequently affected domain was sleep (61%) followed by urinary domain (59%). Mean NMSS score in our study was 28.5 ±22.16. Most commonly observed NMS was difficulty in falling asleep (3.5± 4.4) followed by urinary urgency (3.5± 4.1).

Key Word: parkinson’s disease.