A study of correlation between lipid peroxide and HbA1C in the diabetic patients

 

 

Abstract              Aims and Objectives: To study Correlation between Lipid peroxide and HbA1C in the Diabetic Patients. Methodology: Participants of the study group were selected from the outpatients population of Department of Diabetology, Thanjavur Medical College, Thanjavur. 100 patients were selected for this study. Out of which 50 patients belong to NIDDM and 50 to IDDM group. 50 persons served as healthy control. Un-paired t-test was used for statistical analysis. Result: Overall the Values of Good control (HbAIC <7) Mean ± S.D and Poor control (HbAIC >7) Mean ± S.D were 4.14 ± 0.1 and 4.54±0.17 in IDDM and 4.37 ±0.08 and 4.92±0.33 in NIDDM and in Total DM Cases were 4.26 ±0.15 and 4.73±0.32 i.e. Significantly less in IDDM ( P<0.0001).Average Lipid values for cases With good control (HbAIC < 7) Mean + S.D. were Significantly less and HDL high than With poor control (HbAIC >7) Mean + S.D. (P<0.0001). Conclusion: It is evidenced that the level of MDA is increased in both types of DM. There is significant increase in levels of plasma Total cholesterol, TGL, LDL and VLDL and significant decrease in levels of HDL in both types of DM.

Key Words: Lipid peroxide, IDDM, NIDDM, MDA (Malondialdehyde), Lipid Profile.