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Table of Content - Volume 21 Issue 2 - February 2022


 

Clinical profile of anaemia with special reference to neurological changes at tertiary hospital

 

Neelima S Deshpande1*, Babita M Yadav2, Sudhir Deshmukh3

 

{1Professor & HOD, Department of Medicine} 3Dean, Vilasrao Deshmukh Government Medical College, Latur, Maharashtra, INDIA.

2Speciality Medical Officer, Vishnu Prasad Narayan Desai Hospital, Mumbai, Maharashtra, INDIA.

Email: babi.yadav8@gmail.com

 

Abstract              Background: anaemia is known to cause CNS dysfunction and peripheral nervous system dysfunction. Aims and objectives: purpose of the study was to investigate the effects of anaemia on peripheral motor nerve function. Materials and Methods: A total of 100 patients with anaemia with age more than 12 years from department of medicine were taken as the study group. Patients with history of diabetes mellitus, peripheral nerve disease, pregnant females, and age less than 12 years were excluded from study. The motor nerve conduction parameters i.e. distal latency (DL), amplitude of compound muscle action potential (CMAP) and motor nerve conduction velocity (MNCV) were recorded bilaterally in median, ulnar, post. Tibial and common peroneal nerve using standard protocols. Values from patients were compared before and after treatment. Results: The motor nerve conduction velocities for both the Median and Ulnar nerves were significantly reduced in cases diagnosed as Megaloblastic anaemia. The distal latency for right Median nerve was found to be increased in cases with Megaloblastic anaemia. The nerve conduction parameters i.e. Motor Nerve Conduction Velocity (MNCV) improved significantly for the Median and Common Peroneal nerve after 6 months of treatment. Conclusion: Alteration in nerve conduction parameters in patients of anaemia and improvement in nerve conduction parameters at the end of treatment was reported in the present study.

Key Words: motor nerve conduction velocity (MNCV), compound muscle action potential (CMAP)