Home About Us Contact Us

 

Table of Content - Volume 21 Issue 3 - March 2022


 

Elevated lipid profile in hypothyroidism patients and risk of CAD

 

Suresh Ade1, Deepali Vidhate2, Sandhya Jathar2, Mahesh Padsalge3*, Thomas Becky4, Murarka Arpith5,

Honey Mittal5, Vivek Harikumar5, Vidisha Jariwala5, Thomas James6

 

1Assistant Professor, Department of Medicine, {2Professor, Department of Biochemistry}, {5MBBS Student}, D Y Patil Deemed to Be University School of Medicine and Hospital, Nerul, Navi Mumbai, INDIA.

3Associate Professor, Department of Medicine, 6Department Of Cardiovascular and Thoracic Surgery (CVTS), D Y Patil School of Medicine and Hospital, Nerul, Navi Mumbai, INDIA.

4Professor Head Research, Christ Deemed to Be University, Lavasa, Pune, INDIA.

Email: drmaheshpadsalge@gmail.com

 

Abstract              Background: Hypothyroidism and dysfunctional thyroid gland is one of the major conditions observed in the middle-aged population. It has been observed that females are more prone for hypothyroidism. Further it has also been observed that obesity, deranged lipid profile, high blood sugar and hypertension were the common features in most of the cases. Metabolic syndrome was considered to play a key role in hypothyroidism. Various factors are associated with it and the molecular cascade is not yet very well understood. The aim of the present study is to evaluate the association between the risk of CAD in hypothyroidism. Results: Serum cholesterol were observed high in hypothyroidism cases than controls [250.75 (±40.15)/ 180.32 (±34.42)], triglycerides concentration was also increased in hypothyroidism cases than controls [285.91(±65.55)/ 125.45(±48.86)]. While decreased levels of HDL were observed in hypothyroidism cases than controls. Fasting blood glucose and HbA1c were significantly high in hypothyroidism group as compared to controls. Conclusion: The present study observed high WC, Deranged lipid profile, hyperglycaemia and high BP in hypothyroidism cases than controls.

Key words: Hypothyroidism, Lipid profile, CAD