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Table of Content - Volume 21 Issue 3 - March 2022


 

A study of clinical profile of sepsis in patients admitted in Intensive care unit at tertiary care hospital

 

Chandrakant M Raibhoge1*, Kiran Mali2

 

1Associate Professor, 2Junior Resident, Department of Medicine, Vilasrao Deshmukh Government Medical College, Latur, Maharashtra, INDIA.

Email: cmraibhoge@gmail.com, dr.kiran.mali.2012@gmail.com

 

Abstract              Background: Sepsis is defined as life threatening organ dysfunction caused by a dysregulated host response to infection and Organ dysfunction is newly defined in terms of a change in baseline SOFA (sequential organ failure assessment) score. Present cross-sectional study was conducted with the objective describe clinical profile of sepsis in patients admitted in Intensive care unit at tertiary care hospital. Material and Methods: Present study was single-center, descriptive observational study, conducted in patients, age>14 years, of either gender, having sepsis admitted in ICU. Results: Out of 64 cases, majority of the cases were from 31-40 years and 51-60 years (21.9%). Mean age of the study population was 51.56 ± 19.48 years. Males were predominant (57.8%) with male to female ratio as 1.378:1. Sputum culture was found positive in 24(37.5%) cases followed by urine culture in 17(26.6%), pus culture in 6(9.4%) and CSF as well as biopsy culture found positive in 2 cases each i.e. 3.1%. Streptococcus pneumoniae was predominantly found microorganism (31.3%) followed by E. Coli (28.1%), Staphylococcus aureus (9.4%), Klebsiella pneumoniae (6.3%). Most commonly involved site of infection was lungs (43.8%) followed by urinary bladder (15.6%), kidney (10.9%) and brain (9.4%) cases. Death rate was 42.2% in our study. Mean duration of ICU stay was 5.84±3.16 days. Majority of the patients stayed in ICU for less than 7 days i.e. 39(60.9%) and remaining 25 i.e. 39.1% stayed in ICU for more than 7 days. Conclusion: Sputum and urine cultures were predominantly found to be positive. Most common site of infection was lungs and urinary bladder. Mortality was 42.2%, majority of deaths were in 31-40 years age group, male. In 33.3% of deaths, Streptococcus pneumonae was the predominant causative organism. In almost half of the deaths, sputum culture was positive.

Keywords: sepsis, sputum culture, SOFA score, APACHE score.