Abstract              Background: A seizure (from the latin word “to take possession of”) is a paroxysmal event due to abnormal, excessive, hypersynchronous discharge from an aggregate of central nervous system neurons. Aims and Objectives: To Study Clinicalprofile of Seizure disorders at Tertiary health care center. Methodology: This was a cross-sectional study in 100 patients of seizure disorder in the age group 15 and above years at tertiary health care center of D Y patil hospital general medical department during 2014 to 2015. Result: Out of the 100 patients, 63% were males and 37% were females 91% (91 patients) of the study patients had generalized tonic seizure, 4% (patients) had partial seizure with secondary generalization, 3% (3 patients) had complex partial seizures and 2% (2 patients) had simple partial seizures 65% (65 patients) of the cases, no cause could be found in spite of rigorous investigation and they were termed ‘idiopathic’ or ‘cryptogenic’. 16% (16 patients) of the cases were due to space occupying lesions. 8% (8 patients) had electrolyte imbalance, 6% (6 patients) had metabolic derangements. 3% (3 patients) had post-stroke convulsion, and 2% (2 patients) had hippocampal sclerosis. Conclusion: It can be concluded from our study that most common type was GTS, in most common etiology was idiopathic followed by Space occupying lesion, electrolyte imbalance, metabolic derangements, post-stroke convulsion, hippocampal sclerosis etc.

Key Words: GTS (Generalized Tonic Seizures), Space occupying lesion, electrolyte imbalance, metabolic Seizures, Post-stroke convulsion.