A comparative study of serum magnesium in type II diabetes mellitus patients and non diabetics and its correlation with treatment modality and duration of diabetes

 

Omkar R Patil¹, Sanjay T Thorat^2*, Mayur Kondewar³

 

^1,3Jr. Resident, ²Associate Professor, Department of Medicine Krishna Institute of Medical Sciences, Karad, Maharashtra, INDIA.

Email: omkarpatil5511@gmail.com

 

Abstract              Background: Magnesium (Mg) deficiency is a common problem in diabetic patients. Deficiency of Mg may increase the incidence of diabetes mellitus (DM). In this study, our aim was to evaluate level of serum magnesium in type II DM patients and non diabetic individuals and its correlation with duration of diabetes and treatment modality. Material and Methods: 140 patients of type II diabetes mellitus in patients and out patients of tertiary care hospital between were included in the study. Also 140 non diabetic age and sex matched patients or relatives of patients attending opd during the same period were included in the study under the control group. Results: The mean age of cases was 57.06 ± 12.77 years while age of controls was 56.67 ± 12.7 years. This small difference was statistically not significant. There was no significant difference between mean serum Mg²⁺ values of male and female patients. (‘p’ = 0.18). The mean serum Mg²⁺ level in controls was 1.96 ± 0.18 mg/dl, which was significantly higher than the mean Mg²⁺ level of cases (1.69 ± 0.29 mg/dl). This difference was statistically significant. (‘p’< 0.001). Longer duration of diabetes has statistically significant influence on low levels of serum magnesium in diabetic subjects under study. (X²=15.353, R.R.= 0.46; ‘p’<0.0001). Amongst patients serum magnesium levels are significantly low in insulin treated patients as compared to those with OHA. (X²=5.884, R.R.=1.632, ‘p’=0.01). Conclusion: There is negative correlation between serum magnesium level and duration of diabetes mellitus type II. Serum magnesium levels are significantly low in insulin treated patients as compared to those with OHA.

Key Words: Diabetes mellitus type II, duration of diabetes, serum magnesium, treatment modality.