A study of clinical profile and outcome in the patients admitted with OP poisoning at tertiary health care center

 

Ramdas Bokil

 

Associate Professor, Department of Medicine, MIMSR Medical college and YCR Hospital, Latur, Maharashtra, INDIA.

 

Abstract              Background: Organophosphorous compounds are principally used as pesticides, and their exposure is highly prevalent in developing countries. Aims and Objectives: To Study Clinical profile and outcome in the patients admitted with OP poisoning at tertiary health care center. Methodology: This was a cross-sectional study carried out at the Department of Medicine in the Patients who were admitted to Intensive care unit of Medicine department with history of Organophosphorus poisoning during one-year period i.e. January 2015 to January 2016. Results: The majority of the patients were in the age group of 20-40 were -42.37% followed by 40-50 -23.73%,50-60 -18.64, >60 -11.86, <20 were 3.39%. The majority of the patients were Female i.e. 64.41% followed by Male i.e. 35.59%. The most common complaint was Nausea-90%. Followed by Vomiting in 80 %, Perspiration in 60 %Salivation in 53%, Altered sensorium in 42%, Convulsion–Respiratory difficulty in 35%, Twitching/flickering in 25%, Stool/urine incontinence in 17%. The majority of the patients were with Mild Severity of Poisoning i.e. 37%, followed by Moderate i.e. 15%, and Severe in 7%. As per the outcome of the patients Majority of the patients Survived i.e. 82%, followed by Death in 11% and DAMA in 7%. Conclusion: it can be concluded from our study that the majority of the patients were in the young age group , the most common presenting problem was Nausea , Vomiting, Perspiration, Salivation, Altered sensorium, Convulsion – Respiratory difficulty etc. The death rate was found to be 11%.

Key Word: OP poisoning, Choline esterase, Muscarinic symptoms, Nicotinic symptoms.