v
Home About Us Contact Us

 

Table of Content - Volume 4 Issue 2- November 2016


Carotid intimo-medial thickness in type 2 diabetes and its correlation to coronary risk factors

 

Sanjay T Thorat1, Mayur Kondewar2, Omkar R Patil3*

 

1Associate Professor, 2,3Jr. Resident, Department of Medicine, Krishna Institute of Medical Science, Karad, Maharashtra, INDIA.

Email: mayurkon@gmail.com

 

Abstract              Background: Diabetes mellitus also accelerates atherosclerosis. An increased carotid intimo-medial thickness (CIMT) was observed in type 2 diabetic patients. Furthermore, asymptomatic hyperglycemic subject were shown to have significant IMT in comparison with healthy control Material and Method: 102 Patients reporting in Medicine ward were studied. The study was undertaken with following objectives. Patients of more than 35 years of age with type II diabetes mellitus according to the criteria of World Health Organization (WHO) are included and critically ill patients and type I diabetes mellitus patients are excluded. The study was designed to identify Carotid intimomedial thickness in Type 2 with coronary risk factors. Results: In type-2 DM patients with CHD, the mean R-CIMT was 1.06 ±0.20, mean L-CIMT was 1.09 ± 0.18 and mean of M-CIMT was 1.08 ±0.18.In type-2 DM patients without CHD, the mean R-CIMT was 0.77 ±0.13, mean L-CIMT was 0.82 ± 0.18 and mean of M-CIMT was 0.80 ±0.15.The age was significantly higher in patients with CHD group as compared to patients without CHD (p=0.001). The weight and BMI were also significantly higher in patients with CHD group as compared to patients without CHD (p=0.001). Height and WHR were comparable in both the groups (p>0.05).Similarly, duration of diabetes was significantly higher in patients with CHD group as compared to patients without CHD (p=0.01).R-CIMT, L-CIMT and MCIMT were significantly higher in patients with CHD group as compared to patients without CHD (‘p’=0.001). Conclusion: There is a correlation of carotid intimomedial thickness with coronary risk factors particularly triglyceride and micro-albuminuria. Patients having known hypertensive, high triglycerides and high microalbuminuria are shown to have high carotid intimomedial thickness.IMT of the common carotid artery is an excellent non-invasive measure of generalized atherosclerosis and is also a surrogate marker of coronary artery disease and is a strong independent predictor for new cardiovascular events.

Key Words: Carotid Doppler, carotid intimo-medial thickening, coronary artery disease, diabetes mellitus type2.