Prescribing pattern and adverse drug reactions of anti hypertensive drugs in Kishanganj hospital

 

Simar Deep Singh^1*, Jagmehak Kaur Satyal²

 

Abstract              Irrational drug prescribing is a common practice globally; it results in increased morbidity, mortality and economic burden on society. Drug utilisation studies are an important tool to promote rational prescribing. Methods: The subjects’ screening and recruitment was carried out at the Department of General Medicine, M.G.M Medical College and L.S.K Hospital, Kishanganj, Bihar. The entire study starting from patient recruitment, data collection, data analysis to reporting took about one year starting from 1st March 2015 to 31st February2016. The patients those are diagnosed as a newly hypertensive are entered in this study except those are matched with exclusion criteria. The treatment was started as per advice of the treating Physician. On next visit the other parameters like Lipid Profile, Blood Urea, Serum Creatinine, Thyroid function test, Blood Sugar, Uric Acid, ECG, Echo Cardiography, CBC, are also reviewed along with monitor of blood pressure. Total 500 randomly selected patients, aged from 18 to 69 yrs, those were attend in the outpatients Department of Medicine, during the study period, who are newly diagnosed as hypertensive or previously diagnosed hypertensive but not started the medication were included initially in my study. Result: Age and Sex wise distribution of the study population. Total 219 Patients were diagnosed with essential hypertension who were selected for my study. For each patient the age, gender, age at which hypertension was diagnosed; In our study 121(55.25%) patients were males and 98(44.75%) patients were females ratio was 1:0.80. distribution of mono therapy treatment of the study population. It observed, Patients those were under treatment of CCB -79 (55.24%), Diuretics - 41(28.68%), ACEI - 8 (5.59%), ARB – 8 (5.59%), and β- Blocker -7 (4.89%), out of 143 Patients. Conclusion: This prospective, observational study on assessment of prescribing pattern for hypertension confirmed that mono therapy was prescribed than the combination therapy. Specify with the guidelines, the most frequently prescribed drug class followed by CCB, diuretics, ARBs and ACEI, beta blockers. When considering combination therapy, two drug combination was prescribed. In two drug combination, CCB+Diuretics was mostly prescribed. Regarding the perception of physicians towards JNC 8 guidelines it was found that majority were following JNC 8 guidelines

Key Word: Prescribing pattern, adverse drug reactions.