A study of correlation between alterations of lipid profile with complications of diabetes

 

Sanjay Thorat¹, Mayur Kondewar², Tejas Rane^3*

 

Abstract              Background and objectives: A prospective study was carried out to find the pattern of Dyslipidemia in type - II diabetics in comparison with non diabetic individuals, based on NCEP guidelines and occurrence of vascular complications of type - II diabetes mellitus. Methods: Fifty type - II diabetes mellitus and fifty age and sex matched non diabetic individuals were studied. The labeling of dyslipidemia was based on NCEP guidelines and vascular complication based on history clinical examination and necessary investigation. Results: Dyslipidemia was present in 92% of diabetic patients with LDL dyslipidemia (LDL > 100 mg/dl) in 60%, HDL dyslipidemia (HDL < 35 mg/dl) in 50% and hypertriglyceridemia (TG > 200 mg/dl) in 48%. The mean age was 49.62 ± 5.38 years and duration of diabetes was 6.69 ± 5.30 years. Total cholesterol was 207.62 ± 49.79 mg/dl triglycerides at 229.69 ± 117.87 LDL at 122.04 ± 46.18 and HDL being 35.64 ±9.00 was observed. Conclusion: The alteration of lipid metabolism of type - II diabetics has raised a serious medical concern with respect to vascular complications like coronary artery disease, cerebro vascular diseases and the recommendation of greater routine evaluation of serum lipid profile and its treatment among both newly detected and old cases of type - II diabetes mellitus strongly suggested.

Key words: Lipidprofile; type II diabetes.