Study of left ventricular diastolic dysfunction in preeclampsia patients

 

Balasaheb Eknathrao Karad¹, Shripad Vithalrao Dhanorkar^2*

 

¹Professor and Head, ²Associate Professor, Department of Medicine, Gouri Devi Institute of medical sciences, Rajbandh, Durgapur, West Bengal, INDIA.

Email: karadbalasaheb@gmail.com, svdhanorkar@gmail.com

 

Abstract              Introduction: Preeclampsia is an acute increase in blood pressure during the second half of pregnancy which is short-lived. More than 50% of the women with elevated blood pressure during pregnancy return to normal by 6-12 weeks postpartum Aims and Objectives: To Study Left Ventricular Diastolic Dysfunction in preeclampsia patients. Methodology: After approval from institutional ethical committee this cross-sectional study was carried out in the patients of Preeclampsia referred for the Cardiovascular hemodynamic at tertiary health care centre. All the patients with the written explained consent were enrolled for the study during the one year duration i.e. June 2016 to June 2017. During the one year 25 random patients with preeclampsia and 25 random patients with normal pregnancy were enrolled into the study. All the patients under gone 2-D echocardiographic evaluation thoroughly. The statistical analysis done by unpaired t-test and calculated by SPSS 19 version software. Result: The average age was 29.35± 5.62 and 27.32 ±6.12 Yrs. and BMI was 25.21± 4.12 and 26.12 ± 5.12 which was comparable with each other (p>0.05). The diastolic parameters like E wave, m/s were 0.6123 ± 0.132 and 2.912 ± 0.131 (p>0.05), A Wave, m/s - 0.732 ± 0.231 and 1.342 ± 0.232 (p>0.001), E/A ratio-1.12 ± 0.342 and 2.121 ± 0.652 (p>0.72), E Dec time, ms -121 ± 8.32 and 197.22 ± 52.32 (p>0.01), IVRT, ms-83.52 ± 7.32 and 99.21 ± 9.42 (p>0.01), E VTI, ms-13.12 ± 1.51 and 14.51± 7.21 (p>0.85), A VTI, ms-2.76 ± 0.45 and 7.98 ± 3.1 (p>0.01 ). Conclusion: Cardiac diastolic dysfunction found very common in women with preeclampsia If this cardiovascular dysfunction can be picked by an echocardiography in preeclamptic women, it may be possible to reduce the risk of heart failure by early intervention.

Key Words: Diastolic Dysfunction, preeclampsia patients, heart failure.