Abstract              Background: Left ventricular hypertrophy (LVH) and anemia are highly prevalent in chronic kidney disease (CKD). Anemia may potentiate the adverse effects of LVH on cardiovascular outcomes thereby increasing the risk of morbidity and mortality in chronic kidney disease patients. Objectives: To study the prevalence of anemia and left ventricular hypertrophy and their correlation in chronic kidney disease patients. Methods: The study was conducted on 100 cases of chronic kidney disease (CKD) admitted at Vydehi Institute of Medical Sciences and Research Centre, Bangalore during the year 2014. The cases were divided based on different stages of CKD (stage II-V). Out of 100 cases there were 9 cases in stage II (eGFR - 60-89mL/min/1.73m²), 17 cases in stage III(eGFR - 30-59 mL/min/1.73m²), 32 cases in stage IV(eGFR - 15-29 mL/min/1.73m²), 42 cases in stage V (eGFR <15 mL/min/1.73m²). All cases were subjected to relevant investigations which were noted and analyzed using appropriate statistical methods. Results: Out of 100 cases with chronic kidney disease, maximum patients were in 41-50 years age group with the mean age being 47.7+13.2 years. There were 69 male patients and 31 female patients showing male predominance. The prevalence of anemia in different stages of CKD were 22% in stage II, 64% in stage III, 87.2% in stage IV, 95.2% in stage V (p =0.000). The prevalence of LVH in different stages of CKD were 55.5% in stage II, 76.4% in stage III, 78.1% in stage IV, 97.6% in stage V (p=0.005). There was a significant correlation between anemia and left ventricular hypertrophy with the p value 0.000. Conclusion: In our study, both anemia and left ventricular hypertrophy are highly prevalent in chronic kidney disease (CKD) patients and we found a significant correlation between anemia and LVH in these patients.

Key Words: Anemia; Chronic kidney disease; Left ventricular hypertrophy.