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Table of Content - Volume 6 Issue 3 - June 2017


A study of association of increased level of HbA1c with development of complications of diabetes mellitus at tertiary health care centre

 

Dilip Pandurang Patil

 

Assistant Professor, Department of Medicine, Krishna institute of Medical sciences " Deemed To Be University" Karad

Dist_ Satara-415539, Maharashtra, INDIA.

Email: patilhospitalkarad@gmail.com

 

Abstract              Background: According to the World Health Organization, approximately 180 million people worldwide currently have type 2 DM (formerly called adult-onset diabetes); over 95% of people with diabetes have this form Aims and Objectives: To Study association of increased level of HbA1C with development of complications of Diabetes mellitus at tertiary health care centre. Methodology: This prospective study was undertaken at Krishna Hospital and Medial research Centre, Karad. One hundered patients of Diabetes Mellitus admitted to hospital during an eighteen month period from 1st July 1977 to 31st December 1998 were included in the study. The statistical analysis done by Chi –square test analyzed by SPSS 19 version software. Result: the majority of the patients were in the age group of 51-60 were 34%, 61-70 were 27%, followed by 41-50 were 18%, 31-40 were 7%, 71-80% were 6%, 21-30 were 4%, >80 and <20 were 2%. The IDDM patients were 28% and NIDDM were 72%. The majority of the patients were with HbA1C% >11 (Bad) were 41%, 9.1-11.0 (Poor)-19%, 8.1-9.0 (Fair)-16%, <8 (Good)-24%. The majority of the patients with Macro-vascular complications were present in the patients with HbA1C% >11 i.e. 22% as compared to 4% HbA1C<11 this observed difference is statistically significant. (χ2 = 27.63,df=1,p<0.0001) The majority of the patients with Micro-vascular complications were present in the patients with HbA1C% >11 i.e. 32% as compared to 8% HbA1C<11 this observed difference is statistically significant. (χ2 = 41.92,df=1,p<0.0001). Conclusion: It can be concluded from our study that the micro-vascular and macro-vascular complications were significantly associated with HbA1C% >11.

Key Words: Glycosylated hemoglobin (HbA1C), IDDM (Insulin Dependant Diabetes Mellitus), NIDDM (Non-insulin Dependent Diabetes Mellitus).