A study of association of metabolic syndrome and psoriasis at tertiary health care centre

 

T V Ramana Rao^1*, Prathyusha Y², Ajay Kumar Reddy Bobba³

 

 

Abstract              Background: Psoriasis is now considered as a systemic inflammatory disease. The chronic inflammatory nature of psoriasis has been suggested to be a contributing and potentially independent risk factor for development of MS. Aims and Objectives: To Study association of metabolic syndrome and psoriasis at tertiary health care centre. Methodology: After approval from institutional ethical committee this cross-sectional study was carried out at the department of Skin and VD of a tertiary health care centre during one year period i.e. June 2017 to June 2018 in the patients with Psoriasis were studied. All details of the patients like age, sex etc. were noted. The statistical analysis was done by chi-square test and unpaired t-test, was analyzed by SPSS 18 version. Result: The age distribution both the group was comparable i.e. average age both the group was 7 ±3.16 and 7 ±4.95 respectively. (p>0.05). The male to female ratio in group A was 1.91:1 and in Group B was 1.18: 1 was comparable to each other (p>0.05). The disease duration in patients with Metabolic syndrome was 9±5.12 Yrs. and 4±2.34 Yrs. was significantly higher (t = 5.2546, df = 68, p<0.0001). As per the PASI score the severity of psoriasis was significantly more in the patients with Metabolic syndrome (χ² = 6.898, df=1, p< 0.0086), as per the area of body affected by BSA score; the significantly more area was affected in the patients with metabolic syndrome (χ² =8.289, df=1, p< 0.004). Conclusion: It can be concluded from our study that severity of the psoriasis and area of affected was significantly associated with the Metabolic syndrome.

Key Words: Metabolic Syndrome (MS), Psoriasis Area and Severity Index (PASI), Body surface area (BSA).