Seizures in adult cases of cerebral malaria in rural based teaching hospital – A Review of literature

 

Umesh Babu¹, Nishant T², Venkateshwarlu Nandyala^3*, Sripada Muvvagopal⁴

 

 

Abstract              Background: In adults the incidence of seizure in cerebral malaria varies grossly from around one or two per cent cases of cerebral malaria 80 % in the literature. The study was planned and executed at semi-urban hospital. Materials and Methods: A total of confirmed 1219 cases of malaria admitted in the Department of Internal Medicine, 954patients satisfied the World Health Organization (WHO) criteria of severe malaria guidelines 2010¹¹ with cerebral malaria and admitted in Medical Intensive Care Unit of SVS Medical College Hospital. Detailed history of symptoms and signs and necessary investigations including CT scan or MRI scan and EEG Observations and Results: Out of 1219 cases of malaria admitted in the Department of Internal Medicine, 954patients satisfied the World Health Organization (WHO) criteria of severe malaria guidelines 2010¹ with cerebral malaria. Our study observed convulsion in cerebral malaria in 64 [8.25%] cases had convulsions. Extensive search was done in the literature to know the incidence and outcome of convulsions in severe malaria. Discussion: Malaria is common disease in India. Severe malaria and cerebral malaria are also common in these parts of the country. Though not common feature, convulsions are ominous symptoms of this disease in adults

Key Words: Cerebral malaria, CT/ MRI Brain, EEG, Seizure activity.