A Study of Hormonal assay among adolescent patients with acne between 15 to 20 at tertiary health care centre

 

T V Ramana Rao¹, Kethireddi S Divya^2*, Ajay kumar Reddy Bobba³

 

 

Abstract              Background: Acne vulgaris is a common disorder of the pilosebaceous unit. It means prevalence in adolescence is estimated to be 70-87%. Aims and Objectives: To Study Hormonal assay among adolescent patients with acne between 15 to 20 at tertiary health care centre. Methodology: After approval from institutional ethical committee a cross-sectional study was carried out in the Department of Skin And VD at tertiary health care centre during the one year period i.e. June 2017 to June 2018. All Male and Female patients who came to the OPD of Skin and VD were randomly i.e. 35 patients included over year with written and explained consent similarly 35 patients without Acne were included into the study. The statistical analysis was done by unpaired t-test and calculated by SPSS 19 version. Result: In our study we have found The average age of the patients age was (Yrs.) (Mean±SD) 25± 5.6 and of the Patients without Acne was 27± 4.78 which was comparable (p>0.05,t=1.82, df=68). The majority of the patients with Acne were Females as compared to Patients without Acne the sex ratio was 2.5 : 1 and 0.75 : 1 ; Female : Respectively in Patients with and Without acne this difference was statistically significant ( p<0.01, χ² = 5.833, df=1). This could be explained by the fact that the Acne are produced in combination with PCOD in the females and the hormonal balance also more common in females. The average Serum level of the hormones like LH (mIU/ml) were 13.45 ± 8.21 and 5.12 ± 2.93 (p<0.005,t=5.65,df=68); FSH (mIU/ml) -6.43 ± 3.43 and 4.32 ± 4.12 (p<0.001,t=6.34,df=68), Prolactin (μIU/ml)-421±178.32 and 367.43 ± 115.23 (p<0.05,t=6.34,df=68), Testosterone (mg/ml) - 0.97 ± 0.52 and 0.38 ± 0.17 (p<0.01,t=6.34,df=68) were significantly higher in the patients with Acne as compared to Patients without Acne Conclusion: It can be concluded from our study that the problem of Acne was more common in Females as compared to Males and the hormones like LH, FSH, Prolactin, Testosterone were significantly higher in the patients of Acne as compared to without Acne patients.

Key Words: Hormonal assay, Acne vulgaris, LH (Luteinizing Hormone), FSH (Follicular Stimulating Hormone), Prolactin, Testosterone.