Role of non-HDL cholesterol in assessing the risk of ischemic stroke on established coronary artery disease patients who were on atorvastatin therapy

 

V Rajendran¹, Aruna Ramani^2*

 

Abstract              Atherosclerosis and its sequel are the leading causes of mortality in this world. With increasing prevalence of sedentary life habits and fast food culture early onset obesity are increasing in prevalence. Because of widespread awareness there is increasing use of statin therapy. But still the risk of coronary and cerebrovascular events has not come down. This study was conducted for analysing lipids beyond LDL. The age ranges from 40 to 80 and the study included both sexes. The study was approved by institutional ethics committee. The risk factors associated with, both modifiable like cigarette smoking, alcohol consumption, hypertension, diabetes mellitus and obesity (BMI) and non- modifiable like age, sex, family history was taken into consideration. The risk factors smoking and alcohol were found out by careful history taking. The risk factors DM and HT were detected by past medical history and laboratory routine investigation and BP measurement. The cut off for non HDL cholesterol is generally thirty mg/dl more than LDL cut off values. 38 % of controls had their non-high density lipoprotein cholesterol in the optimal range. But only 20 % of cases had their non HDL cholesterol in the optimal range. The mean non HDL cholesterol among cases is 160.04 mg/dl. The mean HDL cholesterol among controls is 136.64 mg/dl.

Keywords: Non HDL Cholesterol, Ischemic Stroke, Coronary Artery Disease