A study of lipid profile in patients with metabolic syndrome at a tertiary health care centre

 

Ramesh H Kamath¹, M S Rao Nayakar Barre^2*

 

Abstract              Background: Diabetes mellitus (DM), a metabolic disorder caused by impaired insulin secretion, peripheral insulin resistance or both. has become a major public health problem in India. s Aims and Objectives: To Study the lipid profile in patients with Metabolic Syndrome at a tertiary health care centre during a one year period i.e. January 2017 to January 2018. Patients diagnosed with Metabolic syndrome were identified and randomly selected in all age groups. Within the 1 year 50 metabolic syndrome patients (Cases) and age matched 50 normal patients (Controls) were enrolled into the study with written explained consent. All patients underwent lipid profile testing and fasting and post -prandial sugar level as per standard protocol. Statistical analysis was done with unpaired t-test and chi-square test using SPSS version 19 software. Result: In our study we saw that the majority of the patients were in the age group 61-70y – 42%, 50-60y.28%, >70y 10% similarly controls were also 60-70y- 38%, 50-60y -26%, >70y were 8% and hence both the cases and controls were comparable with age (p>0.05). The majority of the patients were male in both groups and male/ female ratios in the both cases and controls were comparable with each other (p>0.05). The mean FBS was significantly higher in cases than control i.e. 168.52±32.23 and 87.65±11.89 (<0.001**), The PPBS mg/dl was 290.23±41.24, 129.62±15.82 (<0.001**). The Total cholesterol mg/dl i.e.210.13±21.78, 192.54±16.94(<0.001**); LDL mg/dl 129.43±12.43, 101.45±12.87 )(p<0.01**); Triglyceride mg/dl-230.42±38.82,142.17±34.52(<0.01**);VLDLmg/dl51. 24±6.72,33.23±3.59 (p<0.001**) was significantly higher in cases as compared to controls and HDL mg/dl was 33.17±7.23 , 45.62±4.52 (p<0.01**) was significantly lesser than controls. Conclusion: It can be concluded from our study that the all patients with metabolic syndrome were having the deranged lipid profile level and that metabolic syndrome was more prevalent in the older age groups and in male patients.

Key Word: Metabolic Syndrome, Type II diabetes, Lipid Profile.