A cross sectional follow-up study of kidney donors in a tertiary care centre from south India

 

 

Abstract              Background: Living renal donors form the major pool of kidney transplantation in India. Even though many studies have demonstrated the safety of living renal donation there is always a concern about safety of renal donors. Materials and method: This was a cross sectional study conducted at Govt. Kilpauk Medical college hospital and Government Royapettah Hospital attached to Govt. Kilpauk Medical College, Chennai. Thirty living related renal donors were included in the study. Their case records were examined for immediate and long term complications. They were examined for HT, IFG, proteinuria, microscopic hematuria. Remnant kidney size was measured using ultra sonogram. Their GFR values were calculated using Cockcroft- Gault, a MDRD and CKD- EPI creatinine formulae. GFR was measured by Tc 99 DTPA isotope scan. Their kidney sizes, calculated and measured GFR were compared with pre-nephrectomy values. Correlation between calculated and measured GFR was assessed. Results: Two donors had hypertension. Five donors had IFG. Two had sub nephrotic proteinuria. Eleven donors had anemia. One developed CKD due to glomerular disease. One died because of malignancy. Donors had expected increase in measured GFR. There were no correlations between calculated eGFR and measured GFR. Conclusion: Even though living renal donation is a safe procedure regular follow up of donors and insistence on life style modifications during each visit is important.

Key Word: Renal donors, measured GFR, e GFR, CKD, proteinuria HT ,IFG.