¹Associate Professor, ²Junior Resident, Department of Medicine, Vilasrao Deshmukh Government Medical College, Latur, Maharashtra, INDIA.

Email: cmraibhoge@gmail.com, dr.kiran.mali.2012@gmail.com

REFERENCES

1. Bone RC, Sprung CL, Sibbald WJ. Definitions for sepsis and organ failure. Crit Care Med 1992; 20:724-6.
2. Vincent J-L, Opal SM, Marshall JC, Tracey KJ. Sepsis definitions: time for change. Lancet 2013; 381:771-4.
3. Ulloa L, Tracey KJ. The “cytokine profile”: a code for sepsis. Trends Mol Med 2005; 11:56-63.
4. Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016;31t:801-10.
5. Lodise TP, Mc Kinnon PS, Swiderski L, Rybak MJ. Outcomes analysis of delayed antibiotic treatment of hospital acquired Staphylococcus bacteremia. Clin Infec Dis 2003;36(11):1418-23.
6. Ullah AR, Hussain A, Ali I, Samad A, Shah ST, Yousef M, Khan TM. A prospective observational study assessing the outcome of Sepsis in intensive care unit of a tertiary care hospital, Peshawar. Pakistan journal of medical sciences. 2016 May;32(3):688.
7. Paary TT, Kalaiselvan MS, Renuka MK, Arunkumar AS. Clinical profile and outcome of patients with severe sepsis treated in an intensive care unit in India. Ceylon Medical Journal. 2016 Dec 27;61(4).
8. Greenberg BM, Atmar RL, Stager CE, Greenberg SB. Bacteremia in the elderly: Predictors of outcome in an urban teaching hospital. J Infect 2005;50:288-95.
9. Grace CJ, Lieberman J, Pierce K, Littenberg B. Usefulness of blood culture for hospitalized patients who are receiving antibiotic therapy. Clin Infect Dis 2001;32:1651-5
10. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med2003; 348:1546-48.
11. Anand AK, Kumar N, Gambhir IS. Clinicomicrobiological profile of the Indian elderly with sepsis. Annals of Tropical Medicine and Public Health. 2016 Sep 1;9(5):316.
12. Leibovici L, Pitlik SD, Konisberger H, Drucker M. Bloodstream infections in patients older than eighty years. Age Ageing 1993;22:431-42
13. Alberti C, Brun-Buisson C, Goodman SV, Guidici D, Granton J, Moreno R, Smithies M, Thomas O, Artigas A, Le Gall JR, European Sepsis Group. Am J Respir Crit Care Med. 2003 Jul 1; 168(1):77-84.
14. Rhodes A, Phillips G, Beale R, Cecconi M, Chiche JD, De Backer D. Intensive Care Med. 2015 Sep; 41(9):1620-8.
15. Peake SL, Delaney A, Bailey M, Bellomo R, Cameron PA, Cooper DJ, et al. Goal directed resuscitation for patients with early septic shock. N Eng J Med. 2014;371(16):1496– 1506
16. Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F et al. A randomized trial of protocol-based care for early septic shock. N Eng J Med. 2014;370(18):1683–1693.
17. Simon F, Rinaldo B, Jeffrey L, et al. Adult-population incidence of severe sepsis in Australian and New Zealand intensive care units. Intensive Care Med 2004; 30: 589-96.
18. Brun-Buisson C, Meshaka P, Pinton P, Vallet B. EPISEPSIS: a reappraisal of the epidemiology and outcome of severe sepsis in French intensive care units. Intensive Care Med 2004; 30: 580-8.
19. Naqvi IH, Mahmood K, Ziaullaha S, Kashif SM, Sharif A. Better prognostic marker in ICU - APACHE II, SOFA or SAP II! Pak J Med Sci. 2016 Sep- Oct;32(5):1146-1151.
20. Faruq MO, Mahmud MR, Begum T, Areef Ahsan ASM, Fatema K Ahmed, et al. A Comparison of Severity Systems APACHE II and SAPS II in Critically ill Patients. Bangladesh Crit Care J. 2013;1:27–32.
21. Freire P, Romãozinho JM, Amaro P, Ferreira M, Sofia C. Prognostic Scores in a Gastroenterology Intensive Care Unit. Rev Esp Enferm Dig. 2010;102:596– 601.