REFERENCES

1. Sharp GC, Irvin WS, Tan EM, et al. Mixed connective tissue disease e an apparently distinct rheumatic disease syndromeassociated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med 1972; 52:148-59.
2. Aringer M, Steiner G, Smolen JS. Does mixed connective tissue disease exist? Yes. Rheum Dis Clin North Am 2005; 31: 411-20.
3. Swanton J, Isenberg D. Mixed connective tissue disease: still crazy after all these years. Rheum Dis Clin North Am 2005; 31:421-36.
4. Sharp GC. MCTD: a concept which stood the test of time. Lupus 2002; 11:333-9.
5. Bennett RM, O'Connell DJ. Mixed connective tissue disease: a clinicopathologic study of 20 cases. Semin Arthritis Rheum 1980; 10:25-51.
6. Nimelstein SH, Brody S, McShane D, Holman HR. Mixed connective tissue disease: a subsequent evaluation of the original 25 patients. Medicine (Baltimore) 1980; 59:239-48.
7. Alpert MA, Goldberg SH, Singsen BH, et al. Cardiovascular manifestations of mixed connective tissue disease in adults. Circulation 1983; 68:1182-93.
8. Sullivan WD, Hurst DJ, Harmon CE, et al. A prospective evaluation emphasizing pulmonary involvement in patients with mixed connective tissue disease. Medicine (Baltimore) 1984; 63:92-107.
9. Sharp GC. Irvin WS, Tan EM, et al: Mixed connective tissue disease: An apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med 52:148-159, 1972
10. Kay DM, Tuianelli DL: Immunofluorescent techniques in clinical diagnosis of cutaneous disease. Ann Intern Med 71:753- 762, 1969
11. Holborow EJ, Weir DM, Johnson CD: A serum factor in lupus erythematosus with affinity for tissue nuclei. Br Med J 2: 732-734, 1957
12. Mayer MM: Complement and complement fixation, In Kabat EA, Mayer MM (Eds): Experimental Immunochemistry, 2nd Ed. Springfield, IL, Charles C Thomas, 1961, p 135
13. Agnello V, Winchester RJ, Kunkel HG: Precipitin reactions of the Clq component of complement with aggregated gammaglobulin and immune complexes in gel diffusion. Immunology 19:909-919, 1970
14. Ginsberg B, Keiser H: A millipore filter assay for antibodies to native DNA in sera of patients with systemic lupus erythematosus. Arthritis Rheum 16:199-207, 1973
15. Stephen D. Prystowsky. Mixed Connective Tissue Disease. West J Med. 1980; 132:288-293.
16. Nakae, K, Furusawa, F, Kasukawa, R, et al. A nationwide epidemiological survey on diffuse collagen diseases: Estimation of prevalence rate in Japan. In: Mixed Connective Tissue Disease and Anti-nuclear Antibodies, Kasukawa, R, Sharp, G (Eds), Excerpta Medica, Amsterdam, 1987. p.9
17. Gilliam JN, Prystowsky SD: Mixed connective tissue disease syndrome-Cutaneous manifestations of patients with epidermal niuclear staining and high titer serum antibody to ribonucleasesensitive extractable nuclear antigen. Arch Dermatol. 1977; 113:583- 587.
18. Hoffman M; Gray RG, Ibuprofen-induced meningitis in mixed connective tissue disease. Clin Rheumatol 1982 Jun; 1(2):128-30.
19. G Narsimulu, Varaprasad. Mixed Connective Tissue Disorders (MCTD). Medicine Update 2010 Vol. 20: 841-5