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Table of Content - Volume 7 Issue 3 - September 2017


 

Efficacy of 0.1% adapalene gel in reducing sebum secretion in patients with mild to moderate acne vulgaris

 

Ajay Govindrao Ovhal1*, Jerajani H R2, Dhurat R S3

 

1Associate Professor, Department of Skin and VD, Government Medical College, Latur-413512, Maharashtra, INDIA.

2Professor and HOD, Department of Dermatology, MGM institute of health sciences, Kamothe, Navi Mumbai, Maharashtra, INDIA.

3Professor and HOD, Department of Dermatology, LTM Medical college and general Hospital Mumbai, Maharashtra, INDIA.

Email: drajayovhal@gmail.com, jerajani@rediffmail.com, rachitadhurat@yahoo.co.in

 

REFERENCES

  1. Leyden JJ. New understandings of the pathogenesis of acne. J Am AcadDermatol. 1995; 32(5 Pt 3):S15–S25.
  2. Brogden RN, Goa KE. Adapalene. A review of its pharmacological properties and clinical potential in the management of mild to moderate acne. Drugs. 1997; 53(3):511–519.
  3. Cunliffe WJ, et al. Clinical efficacy and safety comparison of adapalene gel and tretinoin gel in the treatment of acne vulgaris: Europe and US. multicenter trials. J Am AcadDermatol. 1997; 6(6 Pt 2):S126–S134.
  4. Shalita A, et al. A comparison of the efficacy and safety of adapalene gel 0.1% and tretinoin gel 0.025% in the treatment of acne vulgaris: a multicenter trial. J Am AcadDermatol. 1996; 34(3):482–485.
  5. Gollnick H, Zouboulis CC, Akamatsu H et al. Pathogenesis and pathogenesis related treatment of acne. J Dermatol 1991; 18:489– 99.
  6. Pie´rard-Franchimont C, Pie´rard GE, Saint-Le´ger D, et al. Comparison of the kinetics of sebum secretion in young women with and without acne. Dermatologica 1991;183:120–2.
  7. Park SG, Kim YD, Kim JJ, Kang SH. Two possible classifications of facial skin type by two parameters in Korean women: sebum excretion rate (SER) and skin surface relief (SSR). Skin Res Technol 1999; 5:189–94.
  8. Youn SW, Kim SJ, Hwang IA, Park KC. Evaluation of facial skin type by sebum secretion: discrepancies between subjective description and sebum secretion. Skin Res Technol 2002; 8:168–72.
  9. Percy S H. Safety and efficacy of adapalene gel 0.1% in acne vulgaris: Results of a post-marketing surveillance study. Indian J DermatolVenereolLeprol 2003; 69:277-80.
  10. Cunliffe WJ, et al. A comparison of the efficacy and tolerability of adapalene 0.1% gel versus tretinoin 0.025% gel in patients with acne vulgaris: a meta-analysis of five randomized trials. Br J Dermatol. 1998; 139(Suppl 52):48–56.
  11. Grosshans E, Marks R, Mascaro JM, et al. Evaluation of clinical efficacy and safety of adapalene 0.1% gel versus tretinoin 0.025% gel in the treatment of acne vulgaris, with particular reference to the onset of action and impact on quality of life. Br J Dermatol. 1998; 139(Suppl 52):26–33.
  12. Ellis CN, Millikan LE, Smith EB, et al. Comparision of adalapene 0.1% solution and tretinoin 0.025% gel in topical treatment of acne vulgaris. Br J Dermatol. 1998; 139(Suppl 52):41–7.
  13. Korkut C, Piskin S. Benzoyl peroxide, adapalene, and their combination in the treatment of acne vulgaris. J Dermatol. 2005; 32:169–73.
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