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MedPulse - International Medical Journal, ISSN 2348-2516 E-ISSN: 2348-1897

Volume 1, Issue 2, March 2014 pp 115-118

Research Article

To study the effect of various diabetic treatment regimens on the outcome of TB

Praveen Kumar G S^*, Carlos Noel Menezes^#, Meghalatha T S^**

^*Professor, ^**Lecturer, Department of Biochemistry, Karpaga Vinayaga Medical College and research centre, Karpaga Vinayaga Nagar, Tamil Nadu, INDIA.

Academic Editor : Dr. Bhanap P. L.

Introduction: Tuberculosis has been a major cause of suffering and death since times of immemorial. Similarly diabetes mellitus is also increasing rapidly. Another important challenge is the growing body of evidence suggesting diabetes as a risk factor for new as well as reactivated old TB cases. And the response to DOTS depends on the control of glucose level. Aims and Objective: To study the effect of various diabetic treatment regimens on the outcome of TB. Material and Method: in the present longitudinal study known diabetic patients who were recently diagnosed suffering from tuberculosis were followed till the completion of DOTS. Three groups were formed in the study. Group I consist of patients on only oral hypoglycemic drugs (OHA). Group II consist of patients on combination OHA and insulin. And in group III patients on only insulin were enrolled. Results: it was observed that maximum cure rate was of group I (100%) followed by group II (90%) and group I (80%). Conclusion: Outcome of tuberculosis was better in patients on insulin only as compared to other group of patients (OHA only and combination of OHA and insulin)