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[Abstract] [PDF] [HTML] [Linked References] MedPulse - International Medical Journal, ISSN 2348-2516 E-ISSN: 2348-1897 Volume 1, Issue 8, June 2014 pp 393-395 Research Article Evaluation of serum electrolytes in hypothyroid patients Kavitha M M1, Sunita Pujar2, C S Hiremath3, Shankar Prasad4, Mahanthesh5 1Assistant Professor, 2,3,4Assistant Professor, 5PG, Department of Biochemistry, 3Department of ENT, S. Nijalingappa Medical College and Research Centre and Sri Hanagal Kumareshwara Hospital, Bagalkot, Karnataka, INDIA. Academic Editor : Dr. Bhanap P. L.
Abstract
Introduction: Thyroid hormones influence the water and electrolyte balance in the body. Hypothyroidism affects electrolyte levels but the underlying mechanism is not well understood. The objective is to find out the alterations in serum electrolytes in patients with subclinical hypothyroidism (SH) and overt hypothyroidism (OH) and to compare them with euthyroid subjects and also to assess the correlation between thyroid stimulating hormone (TSH) and serum electrolytes. Material and Methods: The study was conducted in the department of Biochemistry, tertiary care center, North Karnataka. Blood sample were collected from all the participants, thyroid profile and electrolytes were measured. Participants were grouped into, group-1: Euthyroid (n=50), Group-2: SH (n=50) and Group-3: OH (n=50). Results: Our study shows the mean serum sodium, potassium and chloride levels were significantly (p<0.001) lower in SCH and OH when compared to euthyroids. There is a negative correlation between TSH with serum sodium and potassium. Conclusion: The serum sodium, potassium and chloride levels are significantly reduced in subclinical and overt hypothyroidism. Hence early detection and supplementation of the electrolytes in hypothyroidism patients may help in prevention of disease progress.
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