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MedPulse - International Medical Journal, ISSN 2348-2516 E-ISSN: 2348-1897

Volume 1, Issue 8, June 2014 pp 367-372

Research Article

Clinico-pathological study of non-neoplastic skin disorders

Jyoti Singh Rajput¹, Kishor Singh², Surendra Singh³, Amarjeet Singh⁴

¹Resident, Department of Pathology, Lala Lajpat Rai Medical College, Meerut, Uttar Pradesh, INDIA.

²Professor and HOD, ⁴Resident, Department of Dermatology, Venereology and Leprosy, NIMS Medical College, Jaipur-Delhi Highway, Jaipur-303121, Rajasthan, INDIA.

³Associate Professor, Department of Pathology, Heart and General Hospital, Jaipur-303121, Rajasthan, INDIA.

Academic Editor : Dr. Bhanap P. L.

Introduction: A large number of Skin conditions that might present to a dermatologist ranging from acute to chronic,as well as cosmetic problem in daily practice. Many of these diseases can be quickly diagnosed. However some patients need detailed and time consuming investigation to confirm the clinical diagnosis. Skin biopsy probably is the most important ancillary aid to confirm clinical diagnosis. Prevalence of skin diseases varies from country to country and various regions within the same country. The skin lesions among the patients can be classified into various categories according to the morphology of lesion and can be confirmed by skin biopsy. Objective: To study the clinic-pathological pattern of various nonneoplastic lesions of skin and find out the agreement between clinical diagnosis and histopathological examination. Methods: A total of 60 cases of non-neoplastic skin lesions were enrolled for the study. Clinical diagnosis was correlated by histopathological examination with H & E stain. Special stains were used as an when required. Results: Maximum number of cases showed infectious diseases consisting 23(38.33%) cases of all non-neoplastic skin biopsies followed by non-infectious erythematous, papular and squamous diseases consisting of 15(25%) cases, connective tissue diseases and biopsies having non-specific histology constituted 7 cases each (11.67%). Among non-infectious group, there were 4 (6.66%) cases of vesiculobullous and vesiculopustular diseases, and had 2 cases (3.33%) of genodermatoses. 1 case each from the group of folliculitis and cutaneous manifestation of gastrointestinal disease were seen. Conclusion: The overall accuracy of the clinical diagnosis depends upon the clinicopathological correlation and skin biopsy is clearly a worthwhile investigative procedure. Infectious diseases comprised of overwhelming diseases of nonneoplastic disorders in our region.